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Alfa Laval Pharma-line is a high-quality shell-and-tube heat exchanger especially developed to meet the high hygienic demands of the pharmaceutical industry. Flexibility in the design makes it suitable for many hygienic applications, whatever the demands.


The Pharma-line P is used in pharmaceutical water systems;        Water For Injection (WFI) and Purified Water (PW) and for  heating or cooling of pharmaceutical products.

Working principles

The Pharma-line P is designed in accordance with FDA , USP and cGMP requirements. In the Pharma-line P the risk of mixing between the product and the heating or cooling (service) medium is eliminated as a result of the double tube sheet design.

The product flows in the tubes while the service medium flows in a cross flow around the tubes, inside the shell. The service medium is sealed in the shell by the first tube sheet and the second tube sheet seals the product. In the event of a leak, the leakage of either fluid is easily visually detected.

Physical Data

Product wetted steel parts: . . . 316L (seamless tubes)
Gaskets: . . . . . . . . . . . . . . . PTFE (FDA compliance & USP class VI certified)
Connections: . . . . . . . . . . . . Tri-clamp on tube side and flanges on service side (other options available)

Technical Data

Heat transfer area: . . . 0.1 m2 – 8.5 m2, other areas available upon request
Design temperature: . . -15°C to 150°C (available up to 200°C)
Design pressure: . . . . . FV/10 barg, higher pressures available Pressure vessel codes: PED and ASME VIII (stamp as option), Chinese TSG and manufacturing license available
Welding: . . . . . . . . . . according to SS-EN ISO 15614-1, SS-EN287-1, SS-EN1418, ASME IX
Surface finish product wetted parts: . . . . . . . Electropolished down to Ra<0.3µm.
Mechanically polished with Ra<0.8 µm or Ra<0.5 µm.